1*THE 99mTc DIPHOSPHONATE IS NON-SPECIFIC, AND DOES NOT REVEAL ANYTHING ABOUT PATHOLOGY. THE 131I-MIBG IS SPECIFIC, INDICATING A TUMOR OF NEURAL CREST ORIGIN*

2*NOTE THAT TRACER UPTAKE IN LONG BONES IS ALWAYS ABNORMAL ON A MIBG SCAN, SINCE IT INDICATES MARROW INVOLVEMENT*

3*SPECT AT 24 HOURS WITH 123I-MIBG INCREASES THE SENSITIVITY OF LIVER METASTASES DETECTION*